A Phase 2/3, Randomized, Open-Label Study Comparing Oral Ixazomib/Dexamethasone and Oral Pomalidomide/Dexamethasone in Patients With RELAPSED AND/OR REFRACTORY MULTIPLE MYELOMA (RRMM)
STUDY GOAL: To learn whether ixazomib in combination with dexamethasone controls multiple myeloma longer than pomalidomide in combination with dexamethasone in patients with Relapsed Refractory Multiple Myeloma whose disease is resistant to lenalidomide but should be sensitive to proteasome inhibitors. The study is for patients who have already received at least two lines of therapy, including lenalidomide and a proteasome inhibitor, and are resistant to lenalidomide but not resistant to proteasome inhibitors.
YOU MAY BE ELIGIBLE
TO PARTICIPATE IF YOU:
- Are 18 years of age or older
- Have Relapsed and/or Refractory Multiple Myeloma (RRMM)
- Your disease is resistant to lenalidomide
- Have received at least 2 consecutive cycles of bortezomib or carfilzomib, and either:
- Achieved at least a partial response (PR) and did not have progressive disease (PD) during treatment or within 60 days after the last dose
- Had bortezomib and/or carfilzomib intolerance without PD upon the start of the next regimen
- Meet other eligibility criteria
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whom it affects.
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